Gabapentin rau dev: Siv, Siv & Cov Kev Mob Siab (Vet Answer)

Cov txheej txheem:

Gabapentin rau dev: Siv, Siv & Cov Kev Mob Siab (Vet Answer)
Gabapentin rau dev: Siv, Siv & Cov Kev Mob Siab (Vet Answer)
Anonim

Ob peb yam ua rau cov tswv tsiaj xav tias tsis muaj kev pab ntau dua li pom lawv cov tsiaj mob thiab kev txom nyem. Koj xav pab lawv zoo, tab sis koj tsis paub yuav ua li cas.

Gabapentin yog ib qho tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv mob rau tib neeg siv, uas tseem siv tau zoo hauv dev. Ntxiv rau cov ntawv thov no, nws tuaj yeem muab rau cov dev rau lub teeb sedation kom txo tau kev ntxhov siab, tshwj xeeb tshaj yog ua ntej tuaj txog ntawm chaw kho tsiaj.

Cov tshuaj no tuaj yeem siv tau zoo li lossis nchuav rau koj tus dev cov zaub mov. Nws muaj ob peb yam kev phiv, nrog rau feem ntau ntsib yog qaug zog, uas ploj hauv 12 teev.

Gabapentin yog dab tsi?

Gabapentin yog cov tshuaj nquag muaj nyob hauv cov tshuaj xws li Neurontin®, Gralise®, thiab Horizant®. Nws yog ib qho tshuaj tib neeg siv los kho qhov mob ntawm peripheral neuropathy thiab qaug dab peg.

Hauv dev, gabapentin yog siv rau:

  • Tshuaj mob
  • Tshuaj ntsuab
  • Idiopathic qaug dab peg (piv txwv li, muaj ib qho laj thawj tsis paub)
  • Ntshai

Rau qhov mob ntev, gabapentin feem ntau cuam tshuam nrog lwm cov tshuaj uas tsis yog-steroidal anti-inflammatory (NSAIDs) lossis opioids vim nws ua kom lawv cov nyhuv.

Mob mob hauv cov dev uas gabapentin tuaj yeem raug sau tseg suav nrog:

  • mob caj dab ntev
  • Cancer
  • Hyperalgesia (exaggerated rhiab heev rau qhov mob)
  • Allodynia (mob nyob rau hauv ib cheeb tsam ntawm daim tawv nqaij tsis cuam tshuam nyob rau hauv qhov kev txiav txim ntawm harmless stimuli)1

Hais txog kev ntxhov siab hauv dev, gabapentin tau siv zoo los txo kev ntxhov siab ua ntej mus ntsib kws kho tsiaj.

Hom kev ua ntawm gabapentin tsis paub meej. Nws ntseeg tau tias muaj kev cuam tshuam rau cov calcium ion channels hauv lub paj hlwb los ntawm inhibiting cov neurotransmitter glutamate. Yeej, nws hloov txoj kev uas dev lub cev hnov mob. Los ntawm "kev ntxhov siab ntawm cov hlab ntsha," gabapentin tseem tuaj yeem pab tswj kev qaug dab peg2

Thaum muaj mob qaug dab peg, gabapentin ua raws li cov tshuaj neurotransmitter GABA (gamma-aminobutyric acid) thiab pab kom qaug dab peg3 Neurotransmitters yog cov tshuaj lom neeg uas ua rau cov paj hlwb xa mus thoob plaws hauv lub cev. lub cev. Lub luag haujlwm ntawm GABA yog txhawm rau txo cov ntshav siab. Lub ntsiab excitatory neurotransmitter yog glutamate, thaum GABA yog lub ntsiab inhibitory neurotransmitter. Thaum muaj kev tsis sib haum xeeb ntawm excitation thiab inhibition, qaug dab peg, excitotoxicity, thiab cell tuag yuav tshwm sim.

Gabapentin ntsiav tshuaj
Gabapentin ntsiav tshuaj

Gabapentin muab li cas?

Txhua zaus nrog koj tus kws kho tsiaj tham ua ntej muab tshuaj rau koj tus tsiaj, suav nrog gabapentin.

Gabapentin yuav tsum tsuas yog muab los ntawm koj tus kws kho tsiaj thiab muaj nyob rau hauv daim ntawv tshuaj ntsiav, tshuaj qhov ncauj, los yog ntsiav tshuaj. Cov tshuaj no yuav tsum tau muab cia rau hauv qhov chaw qhuav, deb ntawm lub teeb thiab tawm ntawm qhov ncav cuag ntawm cov tsiaj, ntawm qhov kub ntawm 77 ° F (25 ° C).

Kev saib xyuas yuav tsum tau noj nrog cov tshuaj gabapentin hauv qhov ncauj vim tias nws yuav muaj xylitol, cov khoom qab zib uas muaj tshuaj lom rau dev. Txawm hais tias koj tus dev noj tsuas yog ib qho me me ntawm xylitol, nws tseem tuaj yeem ua rau cov ntshav qab zib tsawg, siab tsis ua haujlwm, qaug dab peg, lossis tuag taus.

Gabapentin tuaj yeem noj nrog lossis tsis muaj zaub mov ib mus rau plaub zaug hauv ib hnub. Yog tias koj tsis tuaj yeem muab tshuaj ntsiav lossis ntsiav tshuaj rau koj tus dev, kis, tsoo, thiab sib tov nrog lawv cov zaub mov. Qhov ntau npaum li cas yuav nyob ntawm koj tus tsiaj qhov hnyav thiab qhov xwm txheej / lub hom phiaj uas nws tau muab. Piv txwv li, rau lub teeb sedation, koob tshuaj yuav siab dua yog tias nws tau muab rau nws cov kev tiv thaiv mob.

Txawm li cas los xij, nyob ntawm qhov kev kho mob uas nws tau muab, qhov kev noj tshuaj ib txwm muaj ntawm gabapentin hauv dev yog raws li hauv qab no:

  • Hauv cov dev uas muaj mob ntev, koob tshuaj yog 1.4–5 mg / phaus ib hnub ib zaug. Koj tus kws kho tsiaj tuaj yeem kho qhov koob tshuaj nyob ntawm koj tus dev qhov tshuaj tiv thaiv rau cov tshuaj thiab nws cov txiaj ntsig.
  • Rau cov dev muaj mob convulsions, koob tshuaj yog nyob nruab nrab ntawm 4.5 thiab 13.6 mg / phaus, ib zaug txhua 8-12 teev. Yog tias koj tus dev noj gabapentin rau kev qaug dab peg, tsis txhob tso tseg cov tshuaj tam sim ntawd, vim tias kev tawm dag zog tuaj yeem tshwm sim. Tus kws kho tsiaj yuav pom zoo kom txo koj tus dev koob tshuaj maj mam li ntawm tsawg kawg 7 hnub.
  • Rau cov dev uas muaj kev ntxhov siab, koob tshuaj yog nyob nruab nrab ntawm 2.2 thiab 13.6 mg / phaus, txog li peb zaug hauv ib hnub. Rau cov dev uas muaj kev ntxhov siab los ntawm kev mus ntsib kws kho tsiaj, tus kws kho tsiaj tuaj yeem pom zoo siv gabapentin 2-3 teev ua ntej mus ntsib, thaum nws nyob ntawm qhov siab tshaj plaws (qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav).

Yog tias koj tus dev noj tshuaj antacids xws li Pepcid lossis Prilosec, gabapentin yuav tsum tau noj tsawg kawg 2 teev tom qab noj tshuaj antacid. Cov kws kho tsiaj pom zoo qhov no vim tias cov tshuaj antacid txo qhov nqus ntawm gabapentin thiab ua kom nws tsis zoo.

Yuav ua li cas yog tias koj tsis noj koob tshuaj?

Yog tias koj tsis nco qab muab koj tus dev ib koob, muab rau lawv sai li sai tau thaum koj nco qab. Yog tias qhov koob tshuaj uas tsis tau nyob ze dua rau lub sijhawm teem tseg, hla qhov koob tshuaj uas tsis tau, thiab muab cov tshuaj ntxiv raws li lub sijhawm. Tsis txhob muab ob npaug rau koob.

Puas muaj tshwm sim ntawm Gabapentin

Gabapentin yog ib yam tshuaj muaj kev nyab xeeb nrog ob peb yam kev phiv, uas yog vim li cas nws thiaj li nrov nyob rau hauv ntau lub chaw kho tsiaj.

Cov kev mob tshwm sim feem ntau ntawm gabapentin hauv dev muaj xws li:

  • Drowsiness
  • Poob kev sib npaug (tsis khov kho)
  • Sleepiness
  • Siab sedation
  • mob raws plab

Kuj tseem muaj kev pheej hmoo tias koj tus dev yuav ua xua rau gabapentin, yog li ntawd, koj tus kws kho tsiaj yuav pom zoo rau lwm cov tshuaj. Yog tias koob tshuaj pom zoo los ntawm tus kws kho tsiaj rau qhov mob ntev ua rau koj tus dev tsaug zog, lawv yuav txo cov koob tshuaj kom txog thaum cov kev xav tau tiav.

Hauv cov dev uas muaj kab mob raum lossis kab mob siab, gabapentin yuav tsum tau siv nrog ceev faj vim tias nws yuav siv sijhawm ntev rau lawv kom metabolize cov tshuaj.

gabapentin ntawm txiv kab ntxwv lub raj mis
gabapentin ntawm txiv kab ntxwv lub raj mis

Cov lus nug nquag nug (FAQs)

Gabapentin sai npaum li cas hauv dev?

Cov teebmeem ntawm gabapentin feem ntau pom tau li ntawm 2 teev tom qab siv tshuaj hauv cov tsiaj feem ntau. Nws qhov siab tshaj plaws yog nyob ntawm 2-3 teev tom qab kev tswj hwm. Txawm li cas los xij, rau qee tus tsiaj, lawv cov tswv yuav pom cov teebmeem ntawm gabapentin hauv ib teev.

Puas Gabapentin yog ib qho mob hnyav rau dev?

Gabapentin yog ib qho tshuaj siv tau zoo los ntawm cov kws kho tsiaj hauv kev kho mob ntev. Nws muaj kev phiv tsawg dua li NSAIDs, uas nyob rau lub sijhawm ntev, tuaj yeem ua rau muaj kev phom sij rau tsiaj. Vim li no, qee zaum, gabapentin ua rau txo qis ntawm cov tshuaj NSAIDs.

Puas Gabapentin ua rau Hind ceg qaug zog hauv dev?

Yog tias koj muaj ib tus dev laus lossis tau muab gabapentin ntau dhau rau lawv, cov ceg tsis muaj zog tuaj yeem tshwm sim. Hauv cov tsiaj laus, cov tshuaj tsis metabolize sai npaum li cov tsiaj me. Yog tias koj tus dev laus pom cov tsos mob tshwm sim tom qab noj gabapentin, tus kws kho tsiaj yuav txo qhov koob tshuaj. Nyob rau hauv cov ntaub ntawv ntawm overdose, hu rau tus kws kho tsiaj tam sim ntawd. Kev noj ntau dhau feem ntau tsis ua rau tus tsiaj tuag, thiab cov tsos mob yuav tsum ploj hauv 8-12 teev.

Conclusion

Gabapentin yog ib hom tshuaj tib neeg uas siv tau zoo los kho mob ntev, qaug dab peg, thiab ntxhov siab hauv dev. Cov tshuaj tsuas yog muab los ntawm kws kho tsiaj, thiab qhov koob tshuaj yuav nyob ntawm koj tus dev tus mob. Gabapentin yog cov tshuaj muaj kev nyab xeeb nrog ob peb yam tsis zoo, nrog rau feem ntau yog qaug zog. Yog tias koj tus dev tsaug zog tom qab noj gabapentin, koj tus tsiaj yuav txo qhov koob tshuaj. Hauv cov dev uas muaj kab mob raum lossis kab mob siab, gabapentin yuav tsum tau ceev faj.

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