Cushing tus kab mob cuam tshuam rau dev ib yam li nws tuaj yeem cuam tshuam rau tib neeg. Nws yog ib qho ntawm cov kab mob uas feem ntau ntsib los ntawm cov neeg laus thiab cov dev laus thiab feem ntau tsis pom zoo vim tias muaj pes tsawg tus cim zoo sib xws rau cov txheej txheem kev laus. Cov tsos mob ntawm tus kab mob kuj txawv nyob ntawm tus dev raug mob, uas ua rau kev kuaj mob nyuaj.
Thaum Cushing tus kab mob tuaj yeem cuam tshuam rau dev hauv ntau txoj kev, nws muaj peev xwm ua rau muaj kev phom sij rau lub neej yog tias tswj tsis raug lossis tsis kho. Phau ntawv qhia no yog ib qho kev piav qhia ntawm Cushing tus kab mob hauv dev thiab suav nrog cov laj thawj vim li cas nws tseem ceeb kom ntes nws ntxov.
Cushing's Disease yog dab tsi?
Kuj hu ua Cushing's syndrome lossis hyperadrenocorticism, Cushing's disease feem ntau cuam tshuam rau cov dev ntau dua 8 xyoo. Vim muaj ntau yam cim qhia ntawm cov neeg mob sib txawv thiab lawv qhov pib qeeb, nws feem ntau tsis pom zoo tab sis muaj ntau dua li ntau tus neeg paub. Cushing tus kab mob tseem cuam tshuam rau tib neeg thiab miv, txawm tias tsawg dua.
Tus mob tshwm sim thaum lub cev cortisol ntau dhau lawm. Cortisol kuj tseem hu ua cov tshuaj hormones kev ntxhov siab. Nws yog ib qho ntuj steroid uas lub cev siv los ua kom nws cov metabolism hauv, txo qhov mob, thiab tswj cov qib qabzib, thiab ntshav siab. Nws cuam tshuam lub cev qhov hnyav, cov ntaub so ntswg, thiab cov tawv nqaij mob. cortisol ntau dhau - lossis tsawg dhau - tuaj yeem cuam tshuam rau koj tus dev lub cev, ua rau koj tus dev muaj kev pheej hmoo ntau dua rau kev mob hnyav, thiab ua rau muaj kev phom sij rau lub neej.
Kev tsim tawm ntau dhau ntawm cortisol tuaj yeem tshwm sim los ntawm ntuj tsim, xws li qog ntawm cov qog pituitary lossis qog adrenal. Nws kuj tseem tuaj yeem yog vim kev siv ntev ntawm cov tshuaj steroids siv los kho lwm yam mob uas koj tus dev yuav raug kev txom nyem.
Cushing's Disease yog dab tsi?
Ib feem ntawm qhov laj thawj uas Cushing's Disease feem ntau yuam kev rau cov txheej txheem kev laus ib txwm nyob hauv dev yog qeeb qeeb li ob peb lub cim ntawm tus kab mob. Tsis yog tsuas yog tus mob feem ntau ua tau zoo los ntawm lub sijhawm uas nws raug kuaj xyuas kom raug, tab sis ntau yam ntawm cov cim qhia tau nthuav dav thiab sib txawv nyob ntawm tus dev cuam tshuam. Ntau tus kuj feem ntau suav hais tias tsis muaj feem cuam tshuam.
Cov tsos mob feem ntau ntawm Cushing tus kab mob feem ntau nqhis dej thiab tshaib plab, tab sis muaj ntau lwm tus, suav nrog:
- Hair Loss
- Paj siab heev
- Nyob zoo
- Nyob qab los noj mov, nqhis dej, thiab tso zis
- Urinary tract infections
- Bacterial daim tawv nqaij kab mob
- tawv tawv ntawm lub qhov ntswg thiab pawm pads
- plab plab loj los yog potbelled tsos
Cushing's Disease yog dab tsi?
Cushing's disease feem ntau cuam tshuam rau cov dev laus, feem ntau thaum lawv laus dua 8 xyoo. Muaj peb hom kab mob Cushing, thiab txhua tus cuam tshuam yog vim li cas tus mob loj tuaj, nws mus li cas, thiab kev kho mob los kho lossis tswj cov cim qhia.
Pituitary dependent
Kwv yees li 80–85% ntawm Cushing tus kab mob yog pituitary nyob ntawm, uas txhais tau hais tias cov qog nyob rau ntawm lub caj pas pituitary ntawm lub hauv paus ntawm lub hlwb. Cov qog no tsim ntau cov tshuaj hormones tsim nyog rau lub cev kom ua haujlwm zoo; ib qho yog adrenocorticotrophic hormone (ACTH), uas txhawb nqa cov qog adrenal ua cortisol.
Thaum tus dev muaj tus kab mob Cushing, cov qog ntawm lub caj pas pituitary ua rau muaj kev tsim tawm ntau dhau ntawm ACTH, uas nyob rau hauv lem, nce tus nqi ntawm cortisol ua los ntawm adrenals. Feem ntau, cov qog ntawm lub pituitary yog qhov zoo, tab sis lawv tuaj yeem ua rau muaj teeb meem hauv lub paj hlwb raws li qhov mob tshwm sim.
Adrenal dependent
Adrenal-dependent Cushing's disease tsis tshua muaj tab sis zoo ib yam li pituitary-dependent Cushing's, nws yog vim mob qog. Txawm li cas los xij, es tsis txhob nyob rau ntawm lub caj pas pituitary, cov qog tsim nyob rau hauv cov qog adrenal, uas nyob ib sab ntawm ob lub raum.
Thaum cov qog tuaj yeem ua rau mob hnyav lossis tsis zoo, ob qho tib si txhawb kev tsim cov cortisol los ntawm cov qog adrenal thiab ua rau cov nyiaj ntau dhau. Cov qog feem ntau tuaj yeem raug tshem tawm nrog kev phais kom kho tus mob. Malignant qog, txawm li cas los xij, feem ntau yuav ua rau tuag taus, tshwj xeeb tshaj yog tias cov qog tau metastasized los ntawm lub sijhawm kuaj mob.
Iatrogenic Cushing's Syndrome
Hom thib peb ntawm Cushing's disease yog tshwm sim los ntawm cov tshuaj steroid thiab hu ua iatrogenic Cushing's syndrome. Yog tias koj tus dev tau txais cov tshuaj steroids ntev dhau lawm, nws tuaj yeem ua rau muaj kev cuam tshuam zoo sib xws ntawm cov qog ntawm cov qog pituitary lossis qog adrenal. Tsis zoo li pituitary- thiab adrenal-dependent Cushing tus kab mob, iatrogenic variation yog tib yam uas yuav tiv thaiv tau.
Tham nrog koj tus kws kho tsiaj txog cov kev pheej hmoo cuam tshuam nrog kev siv cov tshuaj steroids ntev, thiab ua haujlwm nrog lawv los tsim cov phiaj xwm los tiv thaiv nws. Los ntawm kev txwv koj kev siv cov tshuaj steroids los kho cov mob uas koj tus dev yuav raug kev txom nyem los ntawm, koj tuaj yeem pab txo qhov kev pheej hmoo ntawm lawv tsim iatrogenic Cushing tus kab mob.
Kuv Yuav Tu Aub Nrog Cushing's Disease Li Cas?
Kev kho mob nyob ntawm hom kab mob Cushing uas koj tus dev tsim. Txawm hais tias nws yuav nyuaj rau ntes nws thaum ntxov, qhov ntxov uas nws tau kuaj pom, qhov zoo dua koj tuaj yeem tswj cov cim thiab ua tiav koj tus dev.
Cov qog pituitary feem ntau yog hom kab mob nyuaj tshaj plaws. Qhov kev hloov pauv no feem ntau yog kho nrog cov tshuaj trilostane thiab mitotane.
Cov qog adrenal yog kho nrog kev phais mob plab uas tshem tawm cov qog. Muab hais tias cov qog yog benign thiab raug tshem tawm tag, tus mob yuav kho tau.
Iatrogenic Cushing's disease yog kho los ntawm kev txiav cov tshuaj steroid uas koj tus dev siv. Nws yog cov txheej txheem qeeb uas cuam tshuam nrog kev txiav koj tus dev tawm ntawm nws cov tshuaj thiab feem ntau ua rau tus kab mob qub raug kho los ntawm cov tshuaj steroids rov tshwm sim.
Dhau li ntawm kev kho mob, Cushing tus kab mob xav kom koj ua tib zoo saib xyuas koj tus dev cov tsos mob thiab kev vam meej. Nws tuaj yeem yog kab mob nyuaj los tswj tab sis nrog kev pab los ntawm koj tus kws kho tsiaj - thiab ob peb yam kev kho mob, koj tus dev tuaj yeem txaus siab rau lub neej zoo. Nrog rau kev kho mob rau hom Cushing tus kab mob uas koj tus dev muaj, koj tuaj yeem pab tswj lawv cov cim los ntawm kev kho koj li cas koj pub lossis noj koj tus dev.
Manage Their Diet
Cov khoom noj muaj txiaj ntsig ntawm koj tus dev noj mov tuaj yeem mus ntev hauv kev pab yooj yim qee yam cim tshwm sim los ntawm kev tsim tawm ntau dhau ntawm cortisol. Nws yuav siv sij hawm ib pliag kom ntseeg tau tias lawv cov zaub mov muaj qhov sib npaug ntawm cov as-ham, tab sis nrog kev ua haujlwm me ntsis, lawv cov zaub mov tuaj yeem pab lawv.
Yog tias lawv muaj tus kab mob Cushing, koj tus dev yuav xav tau kev noj zaub mov kom haum rau lawv cov tsos mob thiab seb tus kab mob cuam tshuam rau lawv li cas. Koj tus kws kho tsiaj tuaj yeem pab ua kom tiav cov nuances ntawm cov zaub mov uas lawv xav tau, tab sis ntawm no yog ob peb yam khoom noj rau cov dev uas muaj tus kab mob no:
- Formulated rau cov laus dev
- Cov rog tsawg, sodium, thiab chloride
- Muaj fiber ntau thiab digestible protein ntau
Tsis txhob txwv dej
Ib yam tshwm sim ntawm Cushing tus kab mob yog nqhis dej ntau. Txij li qhov no feem ntau ua rau ntau zaus potty so, nws tuaj yeem ntxias kom maj mam "txhawb" koj tus dev kom haus tsawg dua los ntawm kev tuav lawv cov dej. Qhov no yeej tsis yog txoj kev coj ncaj ncees.
Thaum nws tuaj yeem ntxhov siab tas li yuav tsum tau ntim cov tais dej tas li thiab lub taub hau sab nraud rau lub lauj kaub tawg, qhov kev daws teeb meem zoo tshaj plaws rau koj tus dev yog tswj tus kab mob kom zoo. Qhov zoo dua koj tswj cov qib cortisol thiab cov cim qhia, lawv yuav haus ntau npaum li cas thiab xav tau kev tso zis tsawg dua.
Txo Kev Siv Steroid
Yog tias koj tus dev raug mob los ntawm iatrogenic Cushing tus kab mob, maj mam txo cov tshuaj steroid uas ua rau nws yog tib txoj kev kho nws. Koj yuav tsum ua raws li koj tus kws kho tsiaj cov lus qhia thaum nws los txiav koj tus dev tawm ntawm nws cov tshuaj thiab npaj kom nws tus mob qub rov qab los.
Puas yog kuv tus dev nqhis dej ntau dhau los ua cim ntawm Cushing's Disease?
Txawm hais tias kev licking ntau dhau tsis suav tias yog ib qho cim tshwj xeeb ntawm Cushing tus kab mob, nws tuaj yeem tshwm sim los ntawm ob peb yam cim qhia tias tus kab mob ua rau. Kev licking ntau dhau tuaj yeem ua rau muaj kab mob ntawm daim tawv nqaij lossis khaus khaus, khaus khaus los ntawm Cushing's. Cov kab mob urinary kuj tuaj yeem ua rau koj tus dev ua tib zoo saib xyuas nws lub nraub qaum dua li niaj zaus vim qhov tsis xis nyob.
Kev licking ntau dhau tsis yog qhia txog tus kab mob Cushing, txawm li cas los xij. Nws yog ib lub tswv yim zoo kom tau txais koj tus dev kuaj los ntawm kws kho tsiaj kom txiav txim siab txog cov teeb meem kev ntxhov siab, kev raug mob, teeb meem hniav, thiab teeb meem xws li OCD.
Cov lus nug nquag nug (FAQs)
Dab Puas Muaj Cushing's Disease Live?
Vim Cushing tus kab mob feem ntau cuam tshuam rau cov dev laus, nws tuaj yeem nyuaj kom paub tseeb tias cov dev tuaj yeem nyob nrog tus kab mob ntev npaum li cas; 2 xyoos yog qhov nruab nrab ntawm lub neej ntawm ntau tus dev uas muaj tus kab mob Cushing, txawm tias ntau tus dev uas muaj tus kab mob no tuag los ntawm qhov tsis sib xws.
Txawm hais tias Cushing's tuaj yeem ua rau muaj teeb meem kev noj qab haus huv hnyav hauv dev, xws li teeb meem raum, nws tsis tas yuav tuag, tshwj xeeb tshaj yog thaum nws ntes tau ntxov thiab tswj kom raug. Nws nyob ntawm seb koj tswj tus kab mob li cas, koj tus dev hnub nyoog npaum li cas, thiab yog tias lawv muaj lwm yam teeb meem kev noj qab haus huv.
Dab Tsiaj Tsiaj Qis Muaj Ntau Yam Rau Cushing's Disease?
Zoo li feem ntau cov teeb meem kev noj qab haus huv hauv dev, qee cov tsiaj txhu muaj kev pheej hmoo ua rau Cushing tus kab mob ntau dua li lwm tus. Qhov no tsis txhais hais tias lwm hom tsiaj yuav tsis tsim teeb meem lossis tias cov tsiaj no yuav raug kev txom nyem los ntawm qhov teeb meem. Txawm li cas los xij, qhov muaj peev xwm nce siab yog tias tus tsiaj twb tau ua tiav los txhim kho tus mob.
Cov dev uas feem ntau raug kev txom nyem los ntawm tus kab mob Cushing muaj xws li:
- Beagle
- Boston Terrier
- Boxer
- Dachshund
- Poodle
Conclusion
Txawm tias tsis tau kuaj pom, tus kab mob Cushing yog ib yam mob uas tuaj yeem cuam tshuam rau cov dev laus. Feem ntau ntawm cov cim qhia feem ntau suav tias yog qhov qub rau cov dev laus, thiab vim tias lawv feem ntau txhim kho qeeb dhau sijhawm, lawv tuaj yeem plam tau yooj yim. Hmoov tsis zoo, kev kuaj mob lig tuaj yeem ua rau kev kho mob thiab kev tswj xyuas tsis zoo thiab ua rau muaj kev pheej hmoo ntawm koj tus dev tsim teeb meem kev noj qab haus huv ntau dua.
